Isaiah 63:10

Isaiah 63:10. But they rebelled, and vexed his holy Spirit therefore he was turned to be their enemy, and he fought against them.

This was a great change in dispensation, though there was no change in the heart of God. He deals roughly with his people when they rebel against him. They would not be improved by tenderness, so now they must be scourged by his rod, and come under his displeasure. When men turn from God, he is "turned to be their enemy."