Matthew 27:33-34

Matthew 27:33-34. And when they were come unto a place called Golgotha, that is to say, a place of a skull, they gave him vinegar to drink mingled with gall: and when he had tasted thereof, he would not drink.

This was a stupefying draught, which was usually given to prisoners about to die in order to mitigate their pain, and therefore Christ would not drink it, for he was determined to suffer even to the bitter end. He had no mitigation of his agony when he was offering his atonement for us; and so, "when he had tasted thereof, he would not drink."